Functional Chitosan by Sougata Jana & Subrata Jana
Author:Sougata Jana & Subrata Jana
Language: eng
Format: epub
ISBN: 9789811502637
Publisher: Springer Singapore
CS-pDNA chitoplexes
Low viscous
pCAGGS-MCS
Influenza
Intranasal
High levels of ion channel protein (M2)- and nucleoprotein (NP)-specific serum IgG and IgA antibodies in mice serum
Sawaengsak et al. (2014)
CS-pDNA nanoparticles
MW 9.3–270 kDa
pVax1-4sFGF-2, pVax1-PDGF-BB
Growth factor therapy
Intramuscular, subcutaneous
High expression of PDPF-BB and FGF-2 with specific antibodies in mice serum, more efficient delivery of plasmids by SC than IM injections
Jean et al. (2009)
Psi-tCS nanoparticles
MW 250 kDa
siRNA
Rheumatoid arthritis
Intravenous
Rapid cellular uptake and excellent in vitro TNF-α gene silencing efficacy, increased accumulation in arthritis joints of mice, IV injections demonstrated inhibition of inflammation and bone erosion in mice model
Lee et al. (2014)
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